Hydroxyapatite (HAP) is a crystalline form of Calcium Phosphate. It is the form made by our bodies, to produce teeth. Our teeth are comprised of 97% Hydroxyapatite (HAP) and only about 1.5% proteins (mainly collagen), and 1.5% water. Using calcium phosphates to promote remineralization and reduce caries has become a large area of study, particularly in Biomimetric Oral Care. (Biomimetric means relating to or denoting synthetic methods which mimic biochemical processes.) See the study, Overview of Calcium Phosphates used in Biomimetic Oral Care, which discusses the remineralization process and the current research on calcium phosphates. Some studies have shown promising results for remineralizing teeth and reducing caries using HAP. However, these studies use synthesized versions of calcium phosphates, including nanoparticles.
Our perspective is this, regarding Hydroxyapatite:
1) Not natural, a processed mineral. Hydroxyapatite is a form of Calcium Phosphate. In its natural state it has low solubility and is not well absorbed or utilized. Dental applications utilize synthesized HAP. Anything synthetic and/or "processed" (just like processed foods) has risks. As a company, we believe in natural ingredients in the most bioavailable form (that your body recognizes) - this is very different from "biocompatible".
2) Not proven safe. In this meta-study (study of studies) from October 2018, titled Opinion of the Scientific Committee on Consumer Safety (SCCS) - Revision of the Opinion on hydroxyapatite (nano) in cosmetic products it is stated “the SCCS considered needle-shaped hydroxyapatite (nano) to be of concern due to its potential toxic effects, and stated that it should not be used in cosmetic products. In terms of other shapes of hydroxyapatite (nano), the available evidence was insufficient to allow drawing a conclusion on the safety of hydroxyapatite (nano) when used in oral cosmetic products up to a concentration of 10%.” It further recommended more studies should be performed to measure the systemic effects. It has not been proven safe. Furthermore, science still does not understand how nano particles impact the body. Here is an article from a a Ph.D. in cell biology and biochemistry about nano particles, and hydroxyapatite.
Synthetic HAP is akin to synthetic Fluoride, with fewer known side effects.
3) Doesn't work with the body's own natural systems for remineralization AND doesn't address the CAUSE of demineralization and caries (excess acidity due to diet). Our bodies are always trying to heal themselves. Giving the body what it needs, and can utilize (most bioavailable form), in the proper amount, with the necessary cofactors, while addressing and correcting the cause (diet and lifestyle) is the sustainable path for optimal health.
We are vitalistic at heart and believe in the body's ability to heal itself when given the right tools. Natural, bioavailable minerals help build strong healthy teeth such as ionic macro minerals and trace minerals. Good sources are plant-based Fulvic Acid, Marine Vegetables (seaweed, algae, kelp), natural living salts (eg. Himalayan, Bamboo, Baja Gold), and Homeopathic Cell Salts (eg. Calc Phos, Silica, Calc Fluor).
We believe in the power of nature.